SF Ali

Pharmacy Unit, Dungun Hospital, 23000, Dungun, Terengganu, Malaysia.

The impact of implementing WMTAC towards anticoagulation treatment in Dungun Hospital

    DOI: 10.52494/ORUR4745
    by AN Alias, SF Ali, W Yusoff, NAS Yahaya, NH Abdul Karim and SA Fadzillah.
    Vol. 5 No. 1 (2019): Malaysian Journal of Pharmacy / Published: December 1, 2019
    Abstract / Full Text / Download PDF

    Abstract

    Objective: The main objective of this study is to compare patients’ outcome in anticoagulation treatment before and after Warfarin Medication Therapy Adherence Clinic (WMTAC). The study compares the cost of INR test between usual care (UC) and WMTAC. The study also determines factors affecting International Normalized Ratio (INR) level among WMTAC patients.

    Methods: A retrospective study involving WMTAC patients was conducted by trained pharmacists at Dungun Hospital. Patients were reviewed by UC for 4 months and continuously followed up by WMTAC for another 4 months were included in this study. Patients who passed away, transferred out and defaulted were excluded from the study. The data were derived from Patient Medical Record and recorded in Warfarin Data Collection Form for analyze.

    Results: The time in therapeutic range (TTR) was 73.46% for WMTAC and 45.58% for UC (p<0.001). The expanded TTR for WMTAC was 90.37% and 61.88% for UC (p<0.001). The percentage of time INR level <1.5 were 0.57% for WMTAC patients and 7.92% for UC patients, while 5.28% UC patients had INR level > 5. The total reagent costs of INR test were MYR 341.04 for WMTAC and MYR 519.40 for UC. The known factors affecting INR level in WMTAC patients were diet (55%), missed dose (36%) and drug interaction (9%).

    Conclusion: According to this study, the WMTAC implementation significantly improved anticoagulation treatment. Besides that, it also beneficial for our reagent cost expenses.